Skeletal System Histology

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Skeletal System 

 HistologyBone is a type of connective tissueRecall CT containsSpecialized cells (in bone)Osteoprogenitor cellsStem cells which divide to produce daugh ...Also important in repair of fracturesFound in the cellular layer of periosteu ...OsteoblastsProduce new bone matrix (osteogenesis)Bone matrix is formed in concentric ring ...Eventually osteoblasts are surrounded by ...OsteocytesMature bone cellsMaintain bone matrixLive in 'little lakes' called lacunaeLacunae are organized in concentric ring ...Lamellae surround central canal (Haversi ...Narrow passageways called canaliculi con ...Projections of osteocytes extend into ca ...This repeating pattern found in compact  ...Note: Spongy bone does not contain osteo ...Instead it is organized in struts and ar ...OsteoclastsNot related to osteoprogenitor cells -co ...Remove bone matrixSecrete enzymes to dissolve bone matrix  ...In living bone, osteoclasts are always r ...Stress put into bone stimulates osteobla ...Immobility reduces bone mass as osteocla ...Extracellular matrixProtein fibers (in bone collagen - accou ...Ground substance (in bone invested with  ...Cacium phosphate (2/3rds weight of bone) ...Cacium salts very hard, but relatively i ...Can withstand compression but are intole ...Collagen fibers are remarkably strong (w ...Flexible - offer resistance to twisting, ...Fibers form framework for Ca salts to fo ...
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Skeletal System

Histology

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Bone is a type of connective tissue
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Recall CT contains
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Specialized cells (in bone)