Epidermis (epithelial tissue, avascular, enervated
5 layers
Stratum Basale
This is where rapid cell division occurs
Stratum Spinosum
Cell division occurs in deepest portion
Stratum Granulosum
Keratinization begins
Stratum Lucidum
Only present in thick skin (palms/soles)
Stratum Corneum
Highly keratinized top layer
Specialized Cells
Dendritic Cells
Phagocytes in stratum spinosum,
communicates with lymphatic system
Tactile Cells
Corresponds with sensory nerve ending in stratum basale
responds to light touch
Melanocytes
Melanin producing cells in stratum basale,
extension project into other layers
Disease related to epidermis
Skin Cancer
Basal Cell
Squamous Cell
Melanoma
Psoriasis
Cells divide more frequently,
results in red patches with silvery scales
Decubitus ulcer
Blood supply occluded
Dermis (connective tissue, vascular, innervated
2 layers
Papillary Region (fingerprints)
Contain dermal papillae, Increase surface area between epidermis,
most abundant in hands and feet
Reticular Layer (dense, irregular connective tissue)
Dense, irregular CT, contains collagen, elastin
connects epidermis to underlying tissue
Contains
Blood vessels
Supply fluid transfer to epidermis, regulate temperature
Muscle fibers
Erector pili muscle cells pull on hair follicle
Other smooth muscle cells move skin
Skeletal muscles anchor to dermis in face
Nerves
Afferent and efferent
Hypodermis/Subcutaneous/Superficial Fascia
loose areolar and/or adipose
Not part of the integument, but often discussed with
Accessory Organs (epithelial tissue)
Hair
Penetrates into the dermis
Nails
Glands
Suderiferous (Sweat)
Merocrine aka Eccrine (water perspiration)
Apocrine (viscous - found in axillary region, groin, areola)
Modified Apocrine
Cereminous (Ear Wax)
Mammary Glands (Breast milk)
Sebaceous (Sebum/Oil)